Gastroesophageal reflux disease (GERD) is a chronic condition that causes uncomfortable heartburn and regurgitation for millions of Americans. Most people with GERD receive relief through daily acid blocking medications called proton pump inhibitors (PPI). However, nearly 30% of PPI users continue to struggle with such burdensome symptoms as regurgitation and nighttime reflux.
If you struggle with GERD and are not getting complete relief from your daily heartburn medications, you may be a candidate for the LESS GERD Clinical Trial. The trial is for EndoStim - an investigational, minimally-invasive procedure that may help improve GERD symptoms.
Gastroesophageal reflux disease (GERD) is the chronic backflow (reflux) of stomach contents into the esophagus. This is often caused by a weak valve, or sphincter, between the esophagus and the stomach. This structure is called the lower esophageal sphincter, or LES. Normally, after you swallow, the LES opens to allow food and liquid to pass into the stomach, and then closes to prevent reflux back into the esophagus. But for people with GERD, this valve is weakened, allowing the digestive juices from the stomach to flow back, or reflux, into the esophagus.
Although acid-blocking medications called proton pump inhibitors (PPI) can help reduce the sensation of heartburn, they do not fix the weakened LES. This causesmany GERD sufferers to have continued symptoms, such as ongoing regurgitationand sleep disruption.
Doctors at select centers are now conducting the LESS GERD Clinical Trial. This trial is for EndoStim - an investigational, minimally-invasive procedure designed to restore normal function to the LES.
EndoStim is a new, minimally-invasive approach to GERD treatment, designed to restore normal function to the lower esophageal sphincter (LES).
The EndoStim system uses a technology called neurostimulation in which two small electrodes connected to a “lead” are placed on the LES. The lead is connected to a small device called a neurostimulator. The neurostimulator and lead deliver mild electrical signals to the LES automatically throughout the day (not normally felt or sensed by the patient). This gentle stimulation is designed to restore normal function to the LES.
The EndoStim system is placed through a minimally-invasive procedure. The device is implanted below the skin. And unlike traditional anti-reflux surgery, the EndoStim procedure is designed to preserve the body’s natural anatomy in order to reduce or avoid gastro-intestinal side effects.
The EndoStim system is currently being offered at select centers through the LESS GERD Clinical Trial.
Video: About GERD & EndoStim